Hypervariant

HYPERVARIANT

Your body evolved for a different world

It has long been assumed a gospel-truth of biology that inflammation rises with age

However it was recently discovered that in Hunter-Gatherer tribes in Malaysia and Bolivia

it does not.

Heart disease, neurodegeneration, & cancer are rare in these populations, despite similar life expectancy.

The research suggests this inflammation pattern is shaped by exposure to modern, industrialized society

If true, this is the most consequential crime against human healthspan of our generation.

Would you like to know
how much you have?

What we measure

An inflammatory signature based on two plasma proteins, reflecting chronic immune activity patterns observed in industrialized populations in Europe, Asia & North America

sTNF-RI

Soluble TNF Receptor I

A circulating decoy receptor (purple), produced by the body when there is a surplus of TNF-α (gray).

IL-6

Interleukin-6

IL-6 is a central immune signalling molecule released in response to cell damage or microbial cues.

What you'll get

A clear picture of where you stand and where you're heading

Inflammation Score

42score
LowTypicalElevated

Score Trajectory Over Time

ElevatedTypicalLow
6mo ago3mo agoToday+6mo+12mo

Projected trajectory based on current trend

Population Distribution

Italian Cohort32nd percentile
n=1,012 • ages 25-75 • mean score 68.2
050100
USA Cohort28th percentile
n=2,847 • ages 30-80 • mean score 72.4
050100
Hypervariant Users18th percentile
n=127 • ages 22-68 • mean score 37.1
050100

Highlighted bar shows your position • Lower = Better

$59
per test

Get your Industrialized-Society Inflammation Score

Compare your score versus population studies from the US & Italy, and with other users

Visit us in downtown San Francisco for a quick, painless blood sample collection experience

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Nonuniversality of inflammaging paper